Pfizer developed and released a contraceptive injectable called Depo-Provera. It's the company's brand name for medroxyprogesterone acetate. This type of birth control involves injecting progestin. This hormone works as a contraceptive by decreasing estrogen levels, thus inhibiting ovulation.
However, recent studies and medical evidence have shown that reduced estrogen levels can also lead to the loss of bone mineral density.
As a result, long-term users of Depo-Provera are at risk of developing osteoporosis, a condition defined by weakened bones that are more vulnerable to fractures.
Depo-Provera does a good job as a birth control by altering the body's natural hormone balance. However, at the same time, this imbalance can lead to bone density loss.
One of the jobs of the hormone estrogen is to maintain healthy bones. It continuously assists in forming new bones to replace old or damaged ones. Lower estrogen levels can lead to bone loss, which ultimately leads to fragile bones that are more likely to break at even the slightest injury.
Loss of bone density sets up individuals to possibly develop osteoporosis in the long run. The following are the common signs and symptoms of osteoporosis, as per the Mayo Clinic:
Women who use Depo-Provera for over a year may experience bone loss early in their lives. And in most cases, there wouldn't be any obvious symptoms. Sadly, this would mean a late diagnosis of osteoporosis.
In Canada, a nationwide class action settlement was reached regarding the connection between Depo-Provera and bone mineral density loss. This 2021 settlement applies to Depo-Provera users before May 31, 2010, who developed osteopenia, osteoporosis, or fragility fractures.
If you used or are currently using Depo-Provera pay attention to your health as one of the major side effects of using Depo-Provera is the development of meningioma of the brain. This condition once diagnosed makes you eligible for financial compensation.